Depends on which class you are playing. A good early weapon for the Huntress/Ranger is Blasticus as it is fair in power and can be used (even in mythical quality) at level 60. As for weapons for Monk, Squire and Apprentice, try to find something that contributes toward the kind of build you are creating with that character (e.g. DPS, Tower, or Hybrid). You may find the High Five a decent Squire weapon (obtainable from the challenge Ogre Crush on difficulties below Insane) though it has a very short range. It all depends on what sort of stats you are looking for, so make sure you check all your weapon drops until you find something that suits you.